Author

Aanya Hirdaramani

Imperial College LondonORCID 0009-0001-9101-1527Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aylin Carla HanyalogluiD· 2 shared Gary Steven FrostiD· 2 shared Chia‐Wei ChengiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersCell Biology

Aylin Carla HanyalogluORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintApr 27, 2026

A fluorescent reporter system for scalable and live detection of PYY production from enteroendocrine cells with single-event resolution

Aanya Hirdaramani, Gary Steven Frost, Aylin Carla Hanyaloglu

This paper develops a fluorescent reporter system to detect PYY secretion from human enteroendocrine cells with single-event resolution, enabling drug discovery for metabolic diseases.

DOI 10.64898/2026.04.24.720392

humanfluorescence / live-cell microscopy

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Molecular BiologybioRxivPreprintJun 14, 2025

A selective and augmentable FFAR2 signal circuitry programs a butyrate-induced cellular identity of enteroendocrine L-cells

Aanya Hirdaramani, Chia‐Wei Cheng, Aylin Carla Hanyaloglu, Gary Steven Frost

The paper shows butyrate activates FFAR2 in L-cells to increase PYY and Pax6, enhancing secretory function through a Gi-dependent pathway without receptor internalization.

DOI 10.1101/2025.06.14.659710

mousehuman

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