GeneticsPLoS GeneticsPeer-reviewed
The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae
Emma B. Alme, Erica J. Stevenson, Nevan J. Krogan…·David Paul Toczyski
This paper identifies Isr1 as a negative regulator of the hexosamine biosynthesis pathway in yeast, showing it inhibits Gfa1 and modulates UDP-GlcNAc synthesis in response to cell cycle and nutrient signals.
6 citations