Cardiac Pacemaker Cells Harness Stochastic Resonance to Ensure Fail-Safe Operation at Low Rates Bordering on Sinus Arrest
Akihiro Okamura, Isabella K. He, Alexander V. Maltsev, Rostislav Bychkov, Syevda Tagirova, Michael Wang, Anna Maltsev, Michael D. Stern, Edward G. Lakatta, Victor A. Maltsev
This study shows cardiac pacemaker cells use stochastic resonance to maintain rhythm at low heart rates, improving reliability in noisy conditions.
Circulation Research · Jul 15, 2026Peer-reviewedBiophysics