Wenlin Hao

This study links LDL-C to cerebral pericyte dysfunction in acute ischemic stroke through clinical and experimental evidence, showing oxidative stress and type-I interferon signaling changes.

This study shows BDNF supports pericyte and vascular health in aging brains by activating Akt signaling to increase PDGFRβ and CD13 expression.

This study shows that gut miRNA depletion in App-knock-in mice alters microbiome composition, reduces Aβ load, and induces anxiety, suggesting miRNA manipulation could influence AD pathogenesis.

This study shows that deleting gut bacteria reduces Alzheimer's pathology in mice by affecting Il-17a and microglial MyD88 signaling.

This study shows that deleting p38-MAPK in myeloid cells reduces Aβ levels and improves cognitive function in APP-transgenic AD mice.