Author

Wenqiang Quan

Tongji UniversityORCID 0000-0002-8243-8078Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Wenlin HaoiD· 4 shared Yang LiuiD· 4 shared Qinghua LuoiD· 3 shared Jing Yang· 2 shared Tomomi FurihataiD· 2 shared Chris Scheffel· 1 shared Dong LiiD· 1 shared En Wang· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersNeuroscience

Wenlin HaoORCID

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4 papers

Recent·Most cited

Low-Density Lipoprotein Cholesterol and Cerebral Pericyte Dysfunction in Acute Ischemic Stroke: Clinical and Experimental Evidence

Feng Wang, Wenqiang Quan, Gang Wu, Jing Yang, Xu Wang, Qian Cao, Wenlin Hao, En Wang, Tomomi Furihata, Weihai Xu, Dong Li, 柯绍发, Yang Liu

This study links LDL-C to cerebral pericyte dysfunction in acute ischemic stroke through clinical and experimental evidence, showing oxidative stress and type-I interferon signaling changes.

bioRxiv · Oct 2, 2026 · PreprintNeuroscience

Brain-derived neurotrophic factor supports pericyte and vascular homeostasis in the aging brain

Qinghua Luo, Wenqiang Quan, Qian Cao, Chris Scheffel, Wenlin Hao, Jing Yang, Tomomi Furihata, Guoping Peng, Zhenyu Tang, Yang Liu

This study shows BDNF supports pericyte and vascular health in aging brains by activating Akt signaling to increase PDGFRβ and CD13 expression.

Acta Neuropathologica Communications · Dec 1, 2025Peer-reviewedNeuroscience

Gut miRNA regulates gut microbiome and Alzheimer pathology in App-knock-in mice

Wenlin Hao, Qinghua Luo, Ilona Magdalena Szabo, Gilles Gasparoni, Sascha Tierling, Wenqiang Quan, Hsin‐Fang Chang, Gang Wu, Julia Maria Schulze-Hentrich, Yang Liu

This study shows that gut miRNA depletion in App-knock-in mice alters microbiome composition, reduces Aβ load, and induces anxiety, suggesting miRNA manipulation could influence AD pathogenesis.

bioRxiv · Jun 5, 2025 · PreprintNeuroscience

Modulation of Alzheimer's Disease Brain Pathology in Mice by Gut Bacterial Deletion: The Role of Il-17a and Microglial MyD88

Wenlin Hao, Qinghua Luo, Inge Tomic, Wenqiang Quan, Tobias Hartmann, Michael Dieter Menger, Klaus C Fassbender, Yang Liu

This study shows that deleting gut bacteria reduces Alzheimer's pathology in mice by affecting Il-17a and microglial MyD88 signaling.

bioRxiv · Dec 6, 2023 · PreprintNeuroscience