Author

Brooke M. Seman

Cold Spring Harbor LaboratoryORCID 0009-0002-0033-744XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Plant Biology· 2

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:plant (other)· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Anat HendelmaniD· 2 shared Blaine FitzgeraldiD· 2 shared Zachary B. LippmaniD· 2 shared Andrea ArronesiD· 1 shared Camila Pinto da CunhaiD· 1 shared Carlos Martí‐GómeziD· 1 shared Danielle CireniD· 1 shared David M. McCandlishiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPlant Biology

Anat HendelmanORCID

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2 papers

Recent·Most cited

A neofunctionalized flowering antagonist created an evolutionary contingency that channeled Solanaceae adaptation

Hagai Shohat, Danielle Ciren, Andrea Arrones, Iacopo Gentile, Srividya Ramakrishnan, Anat Hendelman, Katharine M. Jenike, Nicole L. Brown, Jose Luna-Ramos, Michael J. Passalacqua, James W. Satterlee, B. P. Fitzgerald, Virginia Baraja-Fonseca, Gina M. Robitaille, Brooke M. Seman, , Zachary B. Lippman

The paper shows a neofunctionalized gene in Solanaceae plants became a flowering antagonist, influencing adaptation across species and environments.

bioRxiv · Feb 21, 2026 · PreprintPlant Biology

Cryptic variation fuels plant phenotypic change through hierarchical epistasis

Sophia G. Zebell, Carlos Martí‐Gómez, Blaine Fitzgerald, Camila Pinto da Cunha, Michael Lach, Brooke M. Seman, Anat Hendelman, Simon Sretenovic, Yiping Qi, Madelaine Elisabeth Bartlett, Yuval Eshed, David M. McCandlish, Zachary B. Lippman

The paper identifies cryptic genetic variants in tomato that drive phenotypic change through hierarchical epistasis in a gene regulatory network.

Nature · Jul 9, 2025Peer-reviewedPlant Biology