Reem Alatrash

This study shows that age-dependent PD-1 induction limits IL-2-driven effector T cell responses during La Crosse virus infection in mice, leading to impaired viral control.

This study identifies T cell responses against La Crosse virus structural proteins Gc and N as critical for protection, showing immunization with these antigens improves survival in vulnerable weanling mice.

This study shows that pre-existing YFV-17D immunity reduces DENV-2 infection severity in mice through T cell cross-protection, not antibodies.

This paper develops an RT-RPA assay for La Crosse virus detection, showing high sensitivity and specificity, and reveals age-dependent neuroinvasion patterns in mice.

This study examines age-related differences in immune responses to La Crosse virus infection in mice, showing that adult mice have protective immunity through neutralizing antibodies and cytokine profiles, while weanlings exhibit pathogenic responses.