Author

Lorena Cascarano

Cliniques Universitaires Saint-LucORCID 0009-0002-0712-1844Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Physiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Caroline BouziniD· 2 shared Chantal DessyiD· 2 shared Hrag Esfahani· 2 shared Jean‐Luc BalligandiD· 2 shared Lauriane Y. M. MicheliD· 2 shared Alberto MelecchiiD· 1 shared Amalia GastaldelliiD· 1 shared Axelle E. LoriotiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSystems Biology

Caroline BouzinORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Beige/brown fat-mediated cardiac protection from high-fat diet is dependent on adipocyte beta3-adrenergic receptor

Lorena Cascarano, Lauriane Y. M. Michel, Hrag Esfahani, Delphine De Mulder, Alberto Melecchi, Caroline Bouzin, Axelle E. Loriot, Jérôme Ambroise, Samantha Pezzica, Fabrizia Carli, Silvia Sabatini, Laurent Gatto, Chantal Dessy, Amalia Gastaldelli, Jean‐Luc Balligand

This study shows that adipocyte beta3-adrenergic receptor activation protects against high-fat diet-induced cardiac damage by promoting beige fat formation and adipose-cardiac communication.

bioRxiv · Jul 28, 2026 · PreprintSystems Biology

A matter of food and substrain: obesogenic diets induce differential severity of cardiac remodeling and diastolic dysfunction in C57Bl/6J and C57Bl/6N substrains

Lorena Cascarano, Hrag Esfahani, Pierre Michel, Caroline Bouzin, Chantal Dessy, Jean‐Luc Balligand, Lauriane Y. M. Michel

This study compares cardiac remodeling and diastolic dysfunction in C57Bl/6J and C57Bl/6N mice on obesogenic diets, finding strain-specific responses to diet.

Physiological Genomics · Jul 15, 2024Peer-reviewedPhysiology