Author

Hrag Esfahani

UCLouvain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Assay:metabolomics· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

Chantal DessyiD· 3 shared Alice MarinoiD· 2 shared Caroline BouziniD· 2 shared Christophe BeauloyeiD· 2 shared Isabelle Anne LeclercqiD· 2 shared Jérôme AmbroiseiD· 2 shared Justine Lallement· 2 shared Sébastian BottiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersPhysiology

Chantal DessyORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Beige/brown fat-mediated cardiac protection from high-fat diet is dependent on adipocyte beta3-adrenergic receptor

Lorena Cascarano, Lauriane Y. M. Michel, Hrag Esfahani, Delphine De Mulder, Alberto Melecchi, Caroline Bouzin, Axelle E. Loriot, Jérôme Ambroise, Samantha Pezzica, Fabrizia Carli, Silvia Sabatini, Laurent Gatto, Chantal Dessy, Amalia Gastaldelli, Jean‐Luc Balligand

This study shows that adipocyte beta3-adrenergic receptor activation protects against high-fat diet-induced cardiac damage by promoting beige fat formation and adipose-cardiac communication.

bioRxiv · Jul 28, 2026 · PreprintSystems Biology

skNAC is a Key Driver of Cardiomyocyte Integrity Against Pathological Cardiac Hypertrophy and Heart Failure

Laura Guilbert, Justine Dontaine, Natacha Fourny, Ettore Vanni, Michele Russo, Hugo Vanderroost, Jade Dron, Jérôme Ambroise, Hrag Esfahani, Caroline Bouzin, Younès Achouri, Emilie Hendrickx, Nassiba Menghoum, B. Bearzatto, D. Vertommen, , Luc Bertrand

This study identifies skNAC as critical for maintaining cardiomyocyte integrity and preventing heart failure by regulating proteome homeostasis and metabolic adaptation during pathological hypertrophy.

bioRxiv · Oct 23, 2025 · PreprintPhysiology

Hepatic ADMA/PRMT1 axis regulation is associated with NO-dependent endothelial dysfunction in MASH

Justine Lallement, Sébastian Bott, Hrag Esfahani, Kristian Serafimov, Maxence Henderson, Zoé Benoit, Laurent Dumas, Sultan Al‐Siyabi, Olivier Féron, Isabelle Anne Leclercq, Chantal Dessy

This study investigates how MASH impairs endothelial function via NO-dependent mechanisms and identifies ADMA as a key liver-derived mediator.

bioRxiv · Jun 10, 2025 · PreprintPhysiology

When the liver is in poor condition, so is the heart - cardiac remodelling in MASH mouse models

Sébastian Bott, Justine Lallement, Alice Marino, Evangelos P. Daskalopoulos, Christophe Beauloye, Hrag Esfahani, Chantal Dessy, Isabelle Anne Leclercq

This study examines cardiac remodelling in MASH mouse models, finding adverse structural changes in the heart linked to liver disease, not overfeeding or aging.

Clinical Science · Aug 29, 2024Peer-reviewedPhysiology