Author

Meizhong Jin

AstraZeneca (United Kingdom)ORCID 0009-0002-1304-2544Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew F. JarnuczakiD· 1 shared Andrew ZhangiD· 1 shared Angelo Andres· 1 shared Fiona Pachl· 1 shared Gustavo J. Gutierrez· 1 shared Jonathan Tart· 1 shared Jonathon DeBonisiD· 1 shared Joseph QuinlaniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Andrew F. JarnuczakORCID

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2 papers

Recent·Most cited

Molecular BiologyJournal of Chemical Information and ModelingPeer-reviewedApr 13, 2026

Biophysical Modeling Elucidates Mechanistic Principles for Rational Molecular Glue Design

Seok Joo Chae, Jonathon DeBonis, Joseph Quinlan…·Oleg A. Igoshin

This paper develops a mathematical framework to analyze molecular glues, showing that strong ternary complex binding affinity is key for performance, with degrader performance limited by catalytic efficiency and target half-life.

1 citation

statistical model

𝕏 PostBluesky

BioinformaticsMolecular OmicsPeer-reviewedSep 23, 2025

Network-driven identification of indisulam neo-substrates for targeted protein degradation

Andrew F. Jarnuczak, Orli Yogev, Angelo Andres…·Meizhong Jin

The paper identifies new neo-substrates of the molecular glue indisulam using network analysis and proteomics, validating one candidate through experimental testing.

1 citation

proteomicsstatistical model

𝕏 PostBluesky