MicrobiologybioRxivPreprint
Thirty years of fluconazole therapy selects an azole-resistant Candida albicans isolate with a pre-adapted physiological, metabolic and structural state
Claudia Marcela Parra‐Giraldo, Julio Jesús Estrada‐Valbuena, Yerly Vargas‐Casanova…·Lucía Monteoliva
This study identifies a fluconazole-resistant C. albicans isolate that exhibits metabolic and mitochondrial adaptations after 30 years of antifungal exposure, suggesting new therapeutic targets.
DOI 10.64898/2026.09.19.752827