ImmunologyMolecular Therapy AdvancesPeer-reviewed
Clinical development of gene edited tacrolimus-resistant Treg (FKBP12KO-Treg) to enable simultaneous immunosuppression and support of immune regulation
Ghazaleh Zarrinrad, Lisa-Marie Burkhardt, C. Beltran-Mestres…·Leila Amini
This paper develops gene-edited tacrolimus-resistant Treg cells (FKBP12KO-Treg) for clinical use in transplant recipients, showing they maintain immunoregulatory function while resisting tacrolimus.
2 citationstop 5%