BioengineeringbioRxivPreprint
A Rapidly Excretable, ROS-Scavenging Ionizable Lipid Decouples mRNA Delivery Potency from Toxicity
Yeji Lee, Han Jeong, Eunbin Kim…·Hyukjin Lee
This paper introduces a dual-function ionizable lipid that reduces mRNA toxicity and enhances clearance, achieving high gene editing efficiency in a macular degeneration model.
DOI 10.64898/2026.04.07.716828