BioengineeringbioRxivPreprint
Mechanical history shapes phenotypic plasticity and fibroblast-autonomous 3D remodeling in iPSC-derived cardiac fibroblasts
Huanzhu Jiang, Ganesh Malayath, Austin C. Kellogg…·Nathaniel Huebsch
This study shows that mechanical culture history affects iPSC-derived cardiac fibroblasts' phenotype and TGF-beta1 response, but later passages can alter these effects.
DOI 10.64898/2026.10.20.759862