Author

Takao Tsukahara

Meikai UniversityORCID 0009-0002-3020-8091Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Michael A. SuttoniD· 4 shared Shigeki IwaseiD· 4 shared Alex CheniD· 3 shared Patricia Marie GarayiD· 2 shared Rafi KoheniD· 2 shared Roman J. GigeriD· 2 shared Bo ZhouiD· 1 shared Brendan L M Sutton· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersNeuroscience

Michael A. SuttonORCID

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4 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 28, 2026

RAI1 safeguards fidelity and tempo of human neurodevelopmental gene expression

Bo Zhou, Satabdi Mohanty, Paris Riggle…·Shigeki Iwase

This study shows RAI1 deficiency accelerates human neurodevelopmental gene expression and disrupts lineage programs in neural progenitors.

DOI 10.64898/2026.06.11.731717

NeuroscienceCell ReportsPeer-reviewedMay 21, 2025

Division of labor among H3K4 Methyltransferases Defines Distinct Facets of Homeostatic Plasticity

Takao Tsukahara, Saini Kethireddy, Katherine M. Bonefas…·Michael A. Sutton

This study identifies distinct roles of H3K4 methyltransferases in synaptic scaling, showing that different KMT2 subfamilies are required for upscaling or downscaling.

1 citation

mouseDNA methylation

NeuroscienceCell ReportsPeer-reviewedAug 1, 2020

RAI1 Regulates Activity-Dependent Nascent Transcription and Synaptic Scaling

Patricia Marie Garay, Alex Chen, Takao Tsukahara…·Shigeki Iwase

The paper profiles nascent RNA in neuronal cultures to show activity-dependent transcriptional changes and links RAI1 to synaptic scaling mechanisms.

29 citations

bulk RNA-seqexperimental assay

NeurosciencebioRxivPreprintJul 30, 2020

Small-hairpin RNAs cause target-independent microRNA dysregulation in neurons and elicit global transcriptomic changes

Rafi Kohen, Katherine T. Baldwin, Patricia Marie Garay…·Roman J. Giger

This study shows that shRNAs cause microRNA dysregulation and global transcriptomic changes in neurons, independent of their target.

3 citations

mousebulk RNA-seq