Author

Krupa Sampat

Baylor College of MedicineORCID 0009-0002-3312-3552Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Kyle P. EageniD· 2 shared Benjamin K. Eschle· 1 shared Brittaney A. LeeperiD· 1 shared Carolina Alejandra Martinez Gutierrez· 1 shared Catherine E. HawkinsiD· 1 shared Celeste D. RosencranceiD· 1 shared Christopher Alexander FrenchiD· 1 shared Christopher PonneiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

Kyle P. EagenORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BET BD2 inhibition facilitates SPOP-mediated degradation of chromatin-associated BRD4/BRD4-NUT, a therapeutic vulnerability in NUT carcinoma

Kathleen Bates, Hoang Nguyen, Kyle P. Eagen, Julianna Huang, Prafulla C. Gokhale, Brittaney A. Leeper, Benjamin K. Eschle, Stacey T Gray, Krupa Sampat, Taylor R Durall, Jia Luo, Geoffrey Ira Shapiro, Steven J. Ferrara, Jacob Gillis, Dustin Rogers, , Christopher Alexander French

The paper shows that selective inhibition of BRD4-BD2 promotes SPOP-mediated degradation of BRD4/BRD4-NUT in NUT carcinoma, leading to better therapeutic outcomes than pan-BET inhibition.

bioRxiv · Aug 19, 2026 · PreprintCancer Biology

NSD3 stabilizes nuclear compartmentalization and promotes megabase-scale chromatin interactions

Yi‐Hung Chen, John R. Collette, Krupa Sampat, Ivaylo D Yonchev, Catherine E. Hawkins, Christopher Ponne, Celeste D. Rosencrance, Kyle P. Eagen

The paper identifies NSD3 as a factor that stabilizes nuclear compartmentalization and promotes long-range chromatin interactions in both fusion-positive and fusion-negative cells.

bioRxiv · Feb 10, 2026 · PreprintMolecular Biology

Biological insights and methodological challenges learned from working with a diverse heterotrophic marine bacterial library

Waseem Bashir Valiya Kalladi, Melisa L. Osborne, Helen Scott, Franziska Kratzl, Carolina Alejandra Martinez Gutierrez, Elena J. Forchielli, Natasha Gurevich, Joseline Velasquez-Reyes, Krupa Sampat, Luca Zoccarato, Konrad Herbst, Osnat Weissberg, Hans‐Peter Grossart, Daniel Segrè, Daniel Sher

The paper establishes and characterizes a marine bacterial library, identifying genetic variations, growth patterns, and methodological challenges in strain maintenance and analysis.

bioRxiv · Nov 25, 2025 · PreprintMicrobiology