Author

Alec Loftus

Loyola University ChicagoORCID 0009-0002-3766-5738Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Bin SuniD· 2 shared Peter Michael Kekenes-HuskeyiD· 2 shared Aalaythia HepburniD· 1 shared Brandon Beh Goh BehiD· 1 shared Jonathan A. KirkiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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2 shared papersBiophysics

Bin SunORCID

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2 papers

Recent·Most cited

BiophysicsComputational Modeling of Biomolecular InteractionsPeer-reviewedAug 10, 2026

Prediction of biomolecule kinetics using physics-based Brownian dynamics to data driven machine learning methods

Bin Sun, Alec Loftus, Peter Michael Kekenes-Huskey

The paper reviews Brownian dynamics modeling of biomolecular binding and its integration with machine learning for predicting in vivo kinetics.

1 citation

statistical modelmachine learning (classical)

𝕏 PostBluesky

BiophysicsThe Journal of General PhysiologyPeer-reviewedJul 22, 2025

Molecular mechanisms of GSK3β-driven modulation of ABLIM1 and titin interactions in cardiac muscle

Bin Sun, Alec Loftus, Brandon Beh Goh Beh…·Peter Michael Kekenes-Huskey

This study investigates how phosphorylation of ABLIM1's intrinsically disordered regions modulates its interaction with titin, affecting cardiac muscle contraction.

DOI 10.1085/jgp.202413737

statistical modelcell signaling & trafficking

𝕏 PostBluesky