Gianni Zanardelli

This study compares cell-cycle gene expression dynamics and mRNA kinetics across mouse and human pluripotent systems, revealing species-specific differences in transcriptional complexity and oscillatory control.

This study shows androgen receptor signaling maintains skeletal muscle stem cell quiescence and regenerative capacity, and its loss leads to premature activation and stem cell depletion.

The paper develops SpaceCycle to infer cell-cycle phases and oscillatory gene expression from spatial transcriptomic data, revealing spatial and temporal patterns of proliferation in tumors.