ImmunologybioRxivPreprint
IFN gamma-induced IRF1 synergizes with TLR7 signals to tune the IRF4-IRF8 axis and drive pathogenic effector B cell fate
Eddie‐Williams Owiredu, Ashley J. Denslow, Suki Chen…·Frances E. Lund
The paper shows IRF1 regulates B cell fate by modulating the IRF4-IRF8 axis, promoting pathogenic effector B cells in SLE.