MicrobiologybioRxivPreprint
Mechanistic insights into Phage SSB-activated bacterial Retron-Eco8 immunity
Chao-Guang Ji, Zhuolin Li, Xin-Yang Wei…·Ning Jia
This study reveals the molecular mechanism of Retron-Eco8 immunity by determining cryo-EM structures of the system in inactive and activated states, showing how phage SSB triggers nuclease activation and cell death.
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