USP7 maintains hematopoietic stem cell dormancy and function by stabilizing HMGA2
Antoine Nouhaud, Diaz Anna, Mathieu Bouttier, Quentin Rigaud, Pauline Enfedaque, Hedi Somaï, Sylvie Hébrard, Naïs Prade, Stéphanie Dufrechou, Daniele Musiani, Mariette Matondo, Guillaume P. Andrieu, Marlène Pasquet, Laëtitia Largeaud, Cyril Broccardo, , Christine Didier
This study identifies USP7 as a regulator of hematopoietic stem cell dormancy by stabilizing HMGA2, showing its role in maintaining stem cell function and longevity.
bioRxiv · Jul 3, 2026 · PreprintCell Biology