Guillaume P. Andrieu

This study identifies Epromoters involved in 3D promoter-promoter interactions that regulate gene expression and are critical for T-ALL cell survival.

This study identifies USP7 as a regulator of hematopoietic stem cell dormancy by stabilizing HMGA2, showing its role in maintaining stem cell function and longevity.

This study identifies interchromosomal interactions between chr19 and the CCND1 locus in MCL, linking spatial genome reorganization to disease-specific transcriptional programs.

This study identifies ALDH1A2 as a therapeutic target in T-ALL, showing its essential role in leukemic cell survival and demonstrating potent anti-leukemic activity with Dimate inhibition.

The paper maps EMT transitions through multi-omic profiling, identifies key regulatory factors, and reveals discordance between molecular layers in human mammary epithelial cells.