Author

Amy Hesketh

Centre National de la Recherche ScientifiqueORCID 0009-0002-5413-1359Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:Arabidopsis· 2 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

David LatrasseiD· 2 shared Marie-Noëlle Pouch-PélissieriD· 2 shared Moussa BenhamediD· 2 shared Olivier MathieuiD· 2 shared Thierry PélissieriD· 2 shared Adrien SaliouiD· 1 shared Ángeles Gómez‐ZambranoiD· 1 shared Célie DaSilva· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersGenomics

David LatrasseORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 9, 2025

Transcriptomic and proteomic analysis of quiescent epimastigotes as a resource for investigating Trypanosoma cruzi persistence.

Francisco Olmo, Amy Hesketh, Hayat Hage…·Josephine Abi‐Ghanem

The paper analyzes the transcriptome and proteome of quiescent T. cruzi epimastigotes to understand persistence mechanisms and improve drug development.

DOI 10.1101/2025.09.09.675056

bulk RNA-seqproteomics

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GenomicsNucleic Acids ResearchPeer-reviewedJul 10, 2023

RTEL1 is required for silencing and epigenome stability

Margaux Olivier, Amy Hesketh, Marie-Noëlle Pouch-Pélissier…·Olivier Mathieu

This study shows RTEL1 is essential for transcriptional silencing and maintaining epigenetic marks in Arabidopsis, with loss of RTEL1 leading to altered H3K27me3 and DNA methylation patterns.

6 citations

ArabidopsisDNA methylation

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GenomicsGenome biologyPeer-reviewedNov 24, 2020

DNA polymerase epsilon is a central coordinator of heterochromatin structure and function in Arabidopsis

Pierre Bourguet, Leticia López‐González, Ángeles Gómez‐Zambrano…·Olivier Mathieu

This study shows that DNA polymerase epsilon subunit POL2A is essential for maintaining heterochromatin structure and function in Arabidopsis by preventing replicative stress and regulating epigenetic marks.

22 citations

ArabidopsisDNA methylation

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