David Latrasse

A molecular framework of chromatin extrusion in plants

This study identifies PDS5A as a key regulator of chromatin loop extrusion and TAD-like domains in Arabidopsis, revealing a promoter- and motif-based mechanism for loop anchoring and transcriptional control.

Brassinosteroid receptors reveal conserved features of exon-embedded gene regulation

The paper identifies an exonic enhancer in the BRI1 gene that regulates its expression and development, showing that exon-encoded regulatory information is conserved across plant species.

Role of the tomato MARS1/ROUGH gene encoding a LYSINE-SPECIFIC HISTONE DEMETHYLASE 1 in adventitious root and fruit skin formation

This study identifies the tomato MARS1/ROUGH gene, which encodes a histone demethylase, and shows its role in regulating adventitious root formation and fruit skin development through epigenetic mechanisms.

Transcriptional control of meiotic recombination by the DREAM complex

This study identifies the DREAM complex as a transcriptional regulator of meiotic recombination in Arabidopsis, showing its role in controlling recombination genes and fertility.

Replication-independent eviction of H2B.8 reveals chromatin reprogramming during seed imbibition

The paper shows that H2B.8 eviction during seed imbibition initiates replication-independent chromatin reprogramming in Arabidopsis.

RTEL1 is required for silencing and epigenome stability

This study shows RTEL1 is essential for transcriptional silencing and maintaining epigenetic marks in Arabidopsis, with loss of RTEL1 leading to altered H3K27me3 and DNA methylation patterns.

Distinctive and complementary roles of E2F transcription factors during plant replication stress response

The paper shows E2FA and E2FB transcription factors in Arabidopsis differently contribute to the plant response to DNA replication defects, working cooperatively with SOG1.

DNA polymerase epsilon is a central coordinator of heterochromatin structure and function in Arabidopsis

This study shows that DNA polymerase epsilon subunit POL2A is essential for maintaining heterochromatin structure and function in Arabidopsis by preventing replicative stress and regulating epigenetic marks.