Specialised RNA decay fine-tunes monogenic antigen expression in African trypanosomes
Lianne I. M. Lansink, Htay Mon Aye, Leon Walther, Sophie Longmore, Madeleine Jones, Adam Dowle, João Luís Reis-Cunha, Joana R. Correia Faria
The paper identifies three proteins that negatively regulate ESAG transcripts through specialised RNA decay in Trypanosoma brucei, revealing a novel post-transcriptional regulatory mechanism.
Nature Microbiology · Mar 30, 2026Peer-reviewedMolecular Biology