Nguyen Phuong Khanh Le

This paper validates modified ISA strategies for producing synthetic JEV and WNV DNA fragments, enabling efficient and bacteria-free synthesis of flaviviruses.

This study shows that endogenous ZAP inhibits Zika virus in Vero cells without requiring a type I IFN response and alters global gene expression during infection.

The paper uses ChIRP-MS to identify ZAP-dependent and -independent cellular proteins interacting with Zika virus RNA, revealing potential ZAP co-factors for antiviral activity.