Author

Ivan Trus

International Institute of Molecular and Cell BiologyORCID 0000-0003-2849-5140Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:plant (other)· 1

Frequent Co-Authors

Gracjan MichlewskiiD· 2 shared Prince Pal SinghiD· 2 shared Uladzimir U. KarniychukiD· 2 shared Ahmad Jawad Sabir· 1 shared Brian CoxiD· 1 shared Christine Wuebben· 1 shared Daniel Udenze· 1 shared Eleanor R. GauntiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersMolecular Biology

Gracjan MichlewskiORCID

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4 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 7, 2026

Persistent Japanese encephalitis virus infection in fetuses of an amplifying pig host affects virus genetic heterogeneity and drives transcriptional footprints in offspring

Prince Pal Singh, Ivan Trus, Daniel Udenze…·Uladzimir U. Karniychuk

This study shows that JEV infection in pig fetuses leads to genetic diversity in the virus and transcriptional changes in offspring, suggesting potential for onward transmission and long-term health impacts.

DOI 10.64898/2026.09.05.749582

plant (other)spatial transcriptomics

𝕏 PostBluesky

MicrobiologyVirology JournalPeer-reviewedNov 9, 2024

Endogenous ZAP is associated with altered Zika virus infection phenotype

Nguyen Phuong Khanh Le, Prince Pal Singh, Ahmad Jawad Sabir…·Uladzimir U. Karniychuk

This study shows that endogenous ZAP inhibits Zika virus in Vero cells without requiring a type I IFN response and alters global gene expression during infection.

6 citations

bulk RNA-seqexperimental assay

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Molecular BiologybioRxivPreprintDec 22, 2023

5'-triphosphate guanosine RNAs recruit GTP-binding proteins to suppress RIG-I/IFN type I signaling

Jacek Szymański, Magdalena Wołczyk, Ivan Trus…·Gracjan Michlewski

The paper shows that 5'-pppG RNAs are less immunogenic than 5'-pppA RNAs due to interactions with GTP-binding proteins, which may help viruses and Pol III transcripts evade innate immune detection.

1 citation

humanexperimental assay

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Molecular BiologybioRxivPreprintSep 13, 2021

TRIM25 inhibits Influenza A infection by destabilising its mRNA and is redundant for the RIG-I pathway.

Nila Roy Choudhury, Gregory Heikel, Ivan Trus…·Gracjan Michlewski

This study shows TRIM25 inhibits Influenza A virus by destabilizing its mRNA and is not required for the RIG-I pathway.

2 citations

humanexperimental assay

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