Cell BiologyProceedings of the National Academy of SciencesPeer-reviewed
Multi-scale mitochondrial cristae remodeling links Opa1 downregulation to reduced OXPHOS capacity in aged hearts
Isidora Molina-Riquelme, Gonzalo Barrientos, Leonhard F. Breitsprecher…·Verónica Eisner
This study investigates age-related mitochondrial cristae structural changes in human and mouse hearts, linking Opa1 downregulation to reduced OXPHOS capacity without affecting core subunit levels.