Leonhard F. Breitsprecher

This study shows that different S. aureus isolates trigger unique host transcriptional responses and cell death pathways, with TNF-R1 playing a key role in regulating infection outcomes in U937 cells.

The paper shows that lipid metabolism in mycobacteria is linked to their subcellular location, with FACL6 deletion disrupting lipid handling and reducing intracellular fitness.

This study investigates age-related mitochondrial cristae structural changes in human and mouse hearts, linking Opa1 downregulation to reduced OXPHOS capacity without affecting core subunit levels.