Isidora Molina-Riquelme

Altered dynamics of ATP synthase cause functional irregularities in senescent hiPS-cardiomyocytes

The paper investigates altered ATP synthase dynamics in senescent hiPS-cardiomyocytes, linking structural changes in mitochondria to reduced enzyme activity and impaired cardiac function.

Multi-scale mitochondrial cristae remodeling links Opa1 downregulation to reduced OXPHOS capacity in aged hearts

This study investigates age-related mitochondrial cristae structural changes in human and mouse hearts, linking Opa1 downregulation to reduced OXPHOS capacity without affecting core subunit levels.

OPA1 and disease-causing mutants perturb mitochondrial nucleoid distribution

This study investigates how OPA1 and its disease-causing mutants affect mitochondrial nucleoid distribution using high-resolution microscopy and a novel model.