Author

Michael P. Ludwig

University of Colorado AnschutzORCID 0009-0002-5961-1490Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Kelly D. SullivaniD· 2 shared Lauren N. DunniD· 2 shared Matthew D. GalbraithiD· 2 shared Angela L. RachubinskiiD· 1 shared Belinda A Enriquez Estrada· 1 shared Congwu ChiiD· 1 shared David J. OrlickyiD· 1 shared Dayna TracyiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Kelly D. SullivanORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMar 11, 2025

NF-κB signaling directs a program of transient amplifications at innate immune response genes

Michael P. Ludwig, Jason R. Wilson, Matthew D. Galbraith…·Kelly D. Sullivan

The paper identifies a program of transient site-specific gains (TSSG) producing extrachromosomal DNA (ecDNA) in immune-related genes driven by NF-κB signaling.

DOI 10.1101/2025.03.11.641929

humanDNA methylation

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GeneticsbioRxivPreprintFeb 3, 2022

Interferon receptor gene dosage determines multiple hallmarks of Down syndrome

Katherine A. Waugh, Ross Minter, Jessica A Baxter…·Joaquin Maximiliano Espinosa

The paper shows that correcting interferon receptor gene dosage in a mouse model of trisomy 21 rescues multiple key phenotypes associated with Down syndrome.

13 citations

mousebulk RNA-seq

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