Author

Kelley Moore

University of ChicagoORCID 0009-0002-5970-3096Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:DNA methylation· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Alexandre ChlenskiiD· 3 shared Chuan HeiD· 3 shared Mark A. ApplebaumiD· 3 shared Mohansrinivas ChennakesavaluiD· 3 shared Andrea PiuntiiD· 2 shared Gepoliano S. ChavesiD· 2 shared Rachel TerHaar· 2 shared Sahil VeeravalliiD· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

Alexandre ChlenskiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologyiSciencePeer-reviewedJul 16, 2026

5-hydroxymethylcytosine deposition mediates Polycomb Repressive Complex 2 function in MYCN-amplified neuroblastoma

Mohansrinivas Chennakesavalu, Gabriel L. Lopez, Varsha Gupta…·Mark A. Applebaum

This study shows that 5-hydroxymethylcytosine (5-hmC) and H3K27me3 co-localize on PRC2 target genes in MYCN-amplified neuroblastoma, repressing developmental genes and sensitizing tumors to DNA demethylating agents.

2 citations

humanDNA methylation

𝕏 PostBluesky

GenomicsJCO Precision OncologyPeer-reviewedJan 31, 2024

5-hydroxymethylcytosine profiling of cell-free DNA identifies bivalent genes that are prognostic of survival in high-risk neuroblastoma.

Mohansrinivas Chennakesavalu, Kelley Moore, Gepoliano S. Chaves…·Mark A. Applebaum

The paper identifies bivalent genes in neuroblastoma cell-free DNA associated with poor prognosis in high-risk patients.

13 citations

humanDNA methylation

𝕏 PostBluesky

GenomicsPediatric Blood & CancerPeer-reviewedOct 20, 2023

Adrenergic and mesenchymal signatures are identifiable in cell-free DNA and correlate with metastatic disease burden in children with neuroblastoma

Omar R. Vayani, Maria E. Kaufman, Kelley Moore…·Mark A. Applebaum

The paper identifies adrenergic and mesenchymal signatures in cell-free DNA 5-hmC profiles and shows their correlation with metastatic burden in neuroblastoma patients.

15 citations

humanDNA methylation

𝕏 PostBluesky