Cumulative pregnancy and postnatal environmental exposures impact social behaviour in male mice associated with epigenetic, ribosomal, and immune dysregulation
Morgan C. Bucknor, Brooke A. Keating, Velda Xinying Han, Brian Gloss, Pinki Dey, Nader Aryamanesh, Lee L. Marshall, Mark Evan Graham, Ruwani Dissanayake, Xianzhong Lau, Shrujna Patel, Stela P. Petkova, Anand Gururajan, Russell Clive Dale, Markus J. Hofer
The paper shows that early life environmental exposures in male mice lead to neurodevelopmental behaviors and molecular changes, while females are unaffected.
bioRxiv · Mar 19, 2025 · PreprintDevelopmental Biology