Brian Gloss

This study identifies clonal IEL expansion and epithelial remodelling in RCD1 using single-cell multi-omics, showing distinct immune and epithelial states compared to ACD.

This study uses spatial transcriptomics to identify a 21-gene signature of CTE lesions, highlighting astrocytic activation and extracellular matrix remodeling as key features.

The paper shows that early life environmental exposures in male mice lead to neurodevelopmental behaviors and molecular changes, while females are unaffected.

This study compares two scRNA-seq platforms, 10x Chromium and BD Rhapsody, in complex tissues, finding similar gene sensitivity but differences in mitochondrial content, cell type detection, and ambient noise sources.

The paper identifies over 650,000 i-motif structures in human genomic DNA using immunoprecipitation and sequencing, showing their widespread distribution and association with highly expressed genes and G0/G1 phase upregulated genes.

This study shows that the TB-associated microenvironment suppresses HIV-1 replication and promotes latency in CD4+ T cells from HIV-1 patients.

The paper shows that stronger systemic and liver immune responses improve liver cancer outcomes by reducing tumor burden and correlating with better survival.

This study investigates gene expression dynamics in mouse embryonic stem cells at high temporal resolution, revealing new insights into transcriptional regulation and noncoding RNA roles.

The paper develops a machine-learning algorithm to annotate human splicing branchpoints from genome sequence, identifying 85% of annotated introns and confirming deleterious mutations.