Author

Alexa L. Michel

Memorial Sloan Kettering Cancer CenterORCID 0009-0002-6738-0100Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Jason Stuart LewisiD· 2 shared Abram BelliD· 1 shared David Bauer· 1 shared David BaueriD· 1 shared Edwin C. PrattiD· 1 shared Lukas M. CarteriD· 1 shared Natalia Herrero ÁlvareziD· 1 shared Roberto De GregorioiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersPharmacology & Toxicology

Jason Stuart LewisORCID

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2 papers

Recent·Most cited

Targeted Alpha Therapy with Ac-Macropa-Isatuximab for CD38-positive Hematological Malignancies

Natalia Herrero Álvarez, David Bauer, Alexa L. Michel, Lukas M. Carter, Jason Stuart Lewis

This paper evaluates [225Ac]Ac-Macropa-Isatuximab as a targeted alpha therapy for CD38-positive hematological malignancies, showing significant tumor reduction and survival extension with minimal toxicity.

bioRxiv · Nov 1, 2024 · PreprintPharmacology & Toxicology

Exploring the PET in vivo generator 134Ce as a theranostic match for 225Ac

David Bauer, Roberto De Gregorio, Edwin C. Pratt, Abram Bell, Alexa L. Michel, Jason Stuart Lewis

This paper compares 225Ac and 134Ce-labeled tracers in cancer models to assess their suitability as a theranostic pair, finding that 134Ce's PET imaging is limited by daughter nuclide redistribution.

European Journal of Nuclear Medicine and Molecular Imaging · Jun 28, 2024Peer-reviewedPharmacology & Toxicology