Inherent Specificity and Variation Sensitivity as Quantitative Metrics for RBP Binding
Soon Yi, Shashi Shekhar Singh, Xuan Ye, Rohan Krishna, Vidusha Kothwela, Eckhard Jankowsky, Joseph M. Luna
The paper introduces two metrics to quantify RBP binding specificity and variation sensitivity, showing their correspondence in vitro and in cells, and demonstrating emergent competition properties.
bioRxiv · Mar 28, 2025 · PreprintMolecular Biology