Author

Xuan Ye

UConn HealthORCID 0000-0002-3157-7537Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:Drosophila· 1 Organism:human· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Brenton R. GraveleyiD· 2 shared Gordon CarmichaeliD· 2 shared Yaling LiuiD· 2 shared Brittany A. ElliottiD· 1 shared Christopher L. HolleyiD· 1 shared Eckhard JankowskyiD· 1 shared Jean-Denis BeaudoiniD· 1 shared Joseph M. LunaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenomics

Brenton R. GraveleyORCID

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3 papers

Recent·Most cited

SnoRNA Expression and RNA 2'-O-Methylation in Drosophila melanogaster S2 Cells

Xuan Ye, Yaling Liu, Sara Olson, Lijun Zhan, Gordon Carmichael, Brenton R. Graveley

This study identifies 239 snoRNAs in Drosophila S2 cells and maps 2-O-methylation sites using RibOxi-seq2, revealing widespread Nm modifications in rRNAs and mRNAs.

bioRxiv · May 22, 2026 · PreprintGenomics

Genome-wide profiling of RNA 2'-O-methylation in neurons and identification of orphan snoRNA targets

Xuan Ye, Yaling Liu, Yinzhou Zhu, Sarah A. Alshawi, Brittany A. Elliott, Christopher L. Holley, Jean-Denis Beaudoin, Brenton R. Graveley, Gordon Carmichael

The paper compares RNA 2'-O-methylation patterns in neurons with and without specific snoRNA deletions, identifying new targets of orphan snoRNAs.

bioRxiv · Dec 17, 2025 · PreprintMolecular Biology

Inherent Specificity and Variation Sensitivity as Quantitative Metrics for RBP Binding

Soon Yi, Shashi Shekhar Singh, Xuan Ye, Rohan Krishna, Vidusha Kothwela, Eckhard Jankowsky, Joseph M. Luna

The paper introduces two metrics to quantify RBP binding specificity and variation sensitivity, showing their correspondence in vitro and in cells, and demonstrating emergent competition properties.

bioRxiv · Mar 28, 2025 · PreprintMolecular Biology