Soon Yi

Fine scale structural information substantially improves multivariate regression model for mRNA in-vial degradation prediction

This paper improves mRNA stability prediction by incorporating fine-scale structural metrics into a regression model, achieving better accuracy than existing methods.

Inherent Specificity and Variation Sensitivity as Quantitative Metrics for RBP Binding

The paper introduces two metrics to quantify RBP binding specificity and variation sensitivity, showing their correspondence in vitro and in cells, and demonstrating emergent competition properties.

Mapping RNA-Protein Interactions with Subcellular Resolution Using Colocalization CLIP

This study introduces colocalization CLIP to map RNA-protein interactions with subcellular resolution, revealing location-specific binding preferences of HuR in different compartments.

A selectable, plasmid-based system to generate CRISPR/Cas9 gene edited and knock-in mosquito cell lines

This paper develops a plasmid-based CRISPR/Cas9 system for generating gene-edited and knock-in mosquito cell lines, demonstrating efficient editing of the AGO1 locus.

TMEM41B is a pan-flavivirus host factor

The paper identifies TMEM41B as a host factor required for flavivirus infection and shows SNPs in TMEM41B reduce infection in East Asian populations.