Eckhard Jankowsky

The paper introduces two metrics to quantify RBP binding specificity and variation sensitivity, showing their correspondence in vitro and in cells, and demonstrating emergent competition properties.

This study uses high-resolution optical tweezers to show Ded1p oligomers unwind RNA duplexes in 4-6 bp steps through dynamic protomer assembly and ATP hydrolysis.

This study identifies eif4e1c's role in zebrafish heart development and regeneration by showing its impact on cardiomyocyte metabolism and proliferation through translation regulation.

The paper shows that cells use an adaptive pausing response to survive severe stress by pausing translation and limiting ATP use, followed by recovery through ISR signaling.