Author

Hedele Zeng

Institute of Industrial Science, The University of TokyoORCID 0009-0002-7262-8465Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:dimensionality reduction· 1 Organism:mouse· 1

Frequent Co-Authors

Yukiko T. MatsunagaiD· 3 shared Li‐Kun PhngiD· 2 shared Mingzhao Hu· 2 shared Jun-ichi Kawabe· 1 shared Koji AndoiD· 1 shared Ricard Casanova· 1 shared Takanori Sano· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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3 shared papersBioinformatics

Yukiko T. MatsunagaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mural-VISTA: A tool for mural cell-vessel interaction assessment and multiscale single-cell topo-morphological analysis

Hedele Zeng, Mingzhao Hu, Li‐Kun Phng, Yukiko T. Matsunaga

Mural-VISTA quantifies 3D mural cell morphology and vessel interactions, revealing cell-type specific effects of RhoA activity on branch complexity and solidity.

bioRxiv · Sep 1, 2026 · PreprintBioinformatics

Mural cell contractility regulates vessel diameter by controlling cell morphology and vessel coverage

Mingzhao Hu, Hedele Zeng, Ricard Casanova, Koji Ando, Yukiko T. Matsunaga, Li‐Kun Phng

This study shows that mural cell contractility and morphology jointly regulate vessel diameter in zebrafish, with vSMCs stabilizing diameter and pericytes having a lesser role.

bioRxiv · Jun 10, 2026 · PreprintCell Biology

Spatiotemporal analysis of pericyte-induced dynamics in nascent angiogenic morphogenesis and heterogeneity using a microvessel-on-a-chip platform

Hedele Zeng, Takanori Sano, Jun-ichi Kawabe, Yukiko T. Matsunaga

This paper introduces a microvessel-on-a-chip platform with a novel morphological registration method to analyze spatiotemporal dynamics of pericyte-induced angiogenesis and heterogeneity.

Cell Biomaterials · Jan 1, 2026Peer-reviewedBioengineering