Author

Mingzhao Hu

RIKEN Center for Biosystems Dynamics Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1

Frequent Co-Authors

Li‐Kun PhngiD· 3 shared Hedele ZengiD· 2 shared Yukiko T. MatsunagaiD· 2 shared Anne K. LagendijkiD· 1 shared Beverly Gwen WindhamiD· 1 shared Biplab BhattacherjeeiD· 1 shared Clifford R. JackiD· 1 shared Emily S. LundtiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersCell Biology

Li‐Kun PhngORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mural-VISTA: A tool for mural cell-vessel interaction assessment and multiscale single-cell topo-morphological analysis

Hedele Zeng, Mingzhao Hu, Li‐Kun Phng, Yukiko T. Matsunaga

Mural-VISTA quantifies 3D mural cell morphology and vessel interactions, revealing cell-type specific effects of RhoA activity on branch complexity and solidity.

bioRxiv · Sep 1, 2026 · PreprintBioinformatics

Mural cell contractility regulates vessel diameter by controlling cell morphology and vessel coverage

Mingzhao Hu, Hedele Zeng, Ricard Casanova, Koji Ando, Yukiko T. Matsunaga, Li‐Kun Phng

This study shows that mural cell contractility and morphology jointly regulate vessel diameter in zebrafish, with vSMCs stabilizing diameter and pericytes having a lesser role.

bioRxiv · Jun 10, 2026 · PreprintCell Biology

Diffusion MRI based biomarkers reveal a Prolonged Pre Lesional Phase of Cerebral Small Vessel Disease

Prashanthi Vemuri, Mingzhao Hu, Emily S. Lundt, Michael G. Kamykowski, Robert I. Reid, Terry M. Therneau, Sheelakumari Raghavan, Petrice M. Cogswell, Michael Griswold, Beverly Gwen Windham, Clifford R. Jack, Ronald Carl Petersen, Jonathan Graff‐Radford

The paper identifies that diffusion MRI biomarkers show microstructural damage up to 16 years before white matter hyperintensities in cerebral small vessel disease.

bioRxiv · Mar 6, 2026 · PreprintNeuroscience

Circumferential actomyosin bundles drive endothelial cell deformations to constrict blood vessels

Yan Chen, Núria Taberner, Jason A. da Silva, Vivek Semwal, Biplab Bhattacherjee, Julia Eckert, Igor Kondrychyn, Mingzhao Hu, Nitish Aswani, Guihua Chen, Yasushi Okada, Anne K. Lagendijk, Tatsuo Shibata, Satoru Okuda, Li‐Kun Phng

This study identifies circumferential actomyosin bundles as drivers of endothelial cell deformations that regulate vessel diameter and prevent vascular malformations.

Nature Communications · Dec 27, 2025Peer-reviewedCell Biology