Yukiko T. Matsunaga

The paper shows pulsatile pressure in microvessels enhances solute clearance through strain-dependent poroelasticity in vascularized systems.

Mural-VISTA quantifies 3D mural cell morphology and vessel interactions, revealing cell-type specific effects of RhoA activity on branch complexity and solidity.

This study shows that mural cell contractility and morphology jointly regulate vessel diameter in zebrafish, with vSMCs stabilizing diameter and pericytes having a lesser role.

This paper introduces a microvessel-on-a-chip platform with a novel morphological registration method to analyze spatiotemporal dynamics of pericyte-induced angiogenesis and heterogeneity.

This study uses a microfluidic model to show that senescent fibroblasts cause ECM softening through collagen network reorganization without changing permeability.

This study shows that VEGF-A and VEGF-C co-stimulation induces lymphatic vessel polarization without shear stress, revealing a mechanism involving VEGFR2/VEGFR3 activation and geometrically-encoded stiffness.

This study develops a 3D in vitro system to visualize tumor intravasation of CTC clusters and identifies TGF-β and activin signaling as essential for this process.

The paper shows that intraluminal pressure rapidly strengthens endothelial barriers through actin reorganization and paracellular gap closure, lasting up to 30 minutes.

The paper investigates extravasation mechanisms in metastatic tumors using a 3D microvessel model and time-lapse imaging, revealing vascular remodeling as a key process in polyclonal colonization.