Cell BiologybioRxivPreprint
Capturing Cardiomyocyte Cell-to-Cell Heterogeneity via Shotgun Single Cell Top-Down Proteomics
Fábio Pereira Gomes, Blandine Chazarin, Aleksandra Binek…·John R. Yates
This study introduces a shotgun single-cell top-down proteomics method to profile proteoform diversity in cardiomyocytes, revealing significant molecular heterogeneity across individual cells.
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