Phosphoinositide lipids have bidirectional and spatially distinct roles in filopodial dynamics
Julia Mason, Thomas C. A. Blake, Roshan Ravishankar, Oscar E M Despard, Gaudenz M. Danuser, Jennifer L. Gallop
This study shows phosphoinositide lipids have distinct roles at filopodial tips and bases, affecting actin dynamics and filopodial movement in Xenopus retinal ganglion cells.
bioRxiv · Oct 13, 2025 · PreprintCell Biology