Author
The University of Texas Southwestern Medical CenterORCID 0000-0001-5778-2881Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Mingyu Choi, Roshan Ravishankar, Lihua He…·Klaus M. Hahn
The paper introduces GTPase biosensors that report activity without blocking ligand interactions, revealing feedback mechanisms in Rac1 regulation.
Maíra A. Lima, Abigail Thomas, Roshan Ravishankar…·Louis Hodgson
The paper develops a FRET biosensor to visualize RhoG activity in live cells and shows its spatial relationship with Rac1 during protrusion.
Sandra Pagano, Colline Sanchez, Natasha Cox Cammer…·Louis Hodgson
This study identifies ARHGAP20 as a regulator of cell migration by modulating Rap1A-RhoA signaling coordination through vesicular trafficking.
Gabriel Muhire Gihana, Kushal Bhatt, Bo-Jui Chang…·Gaudenz M. Danuser
This study shows that branched actin-driven membrane protrusions (BAMPs) enhance oncogenic KRAS signaling by amplifying upstream regulators and promoting cell proliferation through merlin inactivation.
Julia Mason, Thomas C. A. Blake, Roshan Ravishankar…·Jennifer L. Gallop
This study shows phosphoinositide lipids have distinct roles at filopodial tips and bases, affecting actin dynamics and filopodial movement in Xenopus retinal ganglion cells.
David Saucier, Xuexia Jiang, Divya Rajendran…·Gaudenz M. Danuser
This paper develops an imaging-based assay using zebrafish larvae to assess organotropism of cancer xenografts and identifies EWSR1::FLI1 and SOX6 as plasticity factors enhancing metastatic adaptability.