Genetic & Genomic MedicinePLoS GeneticsPeer-reviewed
Integrative Mendelian Randomization for Detecting Exposure-by-group Interactions Using Group-Specific and Combined Summary Statistics
Ke Xu, Nathaniel Maydanchik, Bowei Kang…·Lin Chen
The paper introduces int2MR, a Mendelian randomization method for detecting exposure-by-group interactions using GWAS summary statistics, showing its effectiveness in identifying sex- and age-group-specific risk factors for ADHD and Alzheimer's disease.
DOI 10.1371/journal.pgen.1011819