Author

Bowei Kang

University of ChicagoORCID 0000-0001-9093-359XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:GWAS / association mapping· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:fine-mapping· 1

Frequent Co-Authors

Ke Xu· 2 shared Lin CheniD· 2 shared Nathaniel MaydanchikiD· 2 shared Aileen KauffmaniD· 1 shared Brandon L. PierceiD· 1 shared David A. BennettiD· 1 shared Elizabeth TsengiD· 1 shared Fan YangiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Ke Xu

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3 papers

Recent·Most cited

Genetic & Genomic MedicinePLoS GeneticsPeer-reviewedSep 11, 2025

Integrative Mendelian Randomization for Detecting Exposure-by-group Interactions Using Group-Specific and Combined Summary Statistics

Ke Xu, Nathaniel Maydanchik, Bowei Kang…·Lin Chen

The paper introduces int2MR, a Mendelian randomization method for detecting exposure-by-group interactions using GWAS summary statistics, showing its effectiveness in identifying sex- and age-group-specific risk factors for ADHD and Alzheimer's disease.

DOI 10.1371/journal.pgen.1011819

humanGWAS summary statistics

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Developmental BiologyJournal of NeurosciencePeer-reviewedNov 12, 2024

Cell-type-specific splicing of transcription regulators and Ptbp1 by Rbfox1/2/3 in the developing neocortex

Xiangbin Ruan, Kaining Hu, Yalan Yang…·Xiaochang Zhang

The paper identifies cell-type-specific splicing of transcription regulators and Ptbp1 by Rbfox1/2/3 in the developing neocortex, showing differential splicing impacts on neuronal migration and differentiation.

2 citations

mousebulk RNA-seq

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Genetic & Genomic MedicineThe American Journal of Human GeneticsPeer-reviewedJul 24, 2024

An integrative multi-context Mendelian randomization method for identifying risk genes across human tissues

Yihao Lu, Ke Xu, Nathaniel Maydanchik…·Lin Chen

The paper introduces mintMR, a multi-context MR framework that improves causal effect estimation by using consistent eQTLs across tissues and multi-view learning for disease-relevant tissue probabilities.

9 citations

humanDNA methylation

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