Cancer BiologyCancer ResearchPeer-reviewed
The farnesyl transferase inhibitor KO-2806 re-sensitizes relapsing tumors to RAS inhibition
Hetika Vora Patel, Alison Elizabeth Smith, Stacia Chan…·Shivani Malik
This paper identifies mTORC1 activity as a driver of resistance to RAS inhibitors and shows that KO-2806 re-sensitizes resistant tumors to RAS inhibition.
3 citations