Author

Maaike J Roodzant

Leiden University Medical CenterORCID 0009-0002-9714-9735Unclaimed ORCID profile · follow to get notified of new preprints

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Ajie MandalaiD· 1 shared Eelco J.P. de KoningiD· 1 shared Esmay HamminkiD· 1 shared Ezra J. van der WeliD· 1 shared Françoise CarlottiiD· 1 shared Marten A. EngelseiD· 1 shared Twan J. J. de WinteriD· 1 shared Yun Suk ChaeiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

Ajie MandalaORCID

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1 paper

Recent·Most cited

Beta hydroxybutyrate alters beta cell identity and function in human islets

Yun Suk Chae, Ajie Mandala, Twan J. J. de Winter, Esmay Hammink, Ezra J. van der Wel, Maaike J Roodzant, Françoise Carlotti, Marten A. Engelse, Eelco J.P. de Koning

This study shows that R-BHB alters human islet cell composition and identity, while S-BHB does not, suggesting ketone metabolism influences beta cell function.

bioRxiv · Dec 26, 2025 · PreprintCell Biology