Marten A. Engelse

This study tests partial decellularization of kidneys using SDS during perfusion to remove donor endothelium, finding it removes endothelial cells but impairs renal function.

This study shows that R-BHB alters human islet cell composition and identity, while S-BHB does not, suggesting ketone metabolism influences beta cell function.

The paper constructs a single-cell multiomics atlas of the human pancreas across development, health, and T2D, identifying plastic cell states and lineage trajectories.

This study shows that normothermic kidney preservation with red blood cells causes iron accumulation and ferroptosis, leading to kidney injury, and suggests alternatives to mitigate these effects.

This study examines how co-culturing pancreatic islets with adipose-derived stromal cells alters their secretome under various stress conditions, revealing potential mechanisms for enhanced islet function and regenerative capacity.